The administration of the GnRH antagonist, cetrorelix, to ooctye donors simplifies oocyte donation
نویسندگان
چکیده
منابع مشابه
The administration of the GnRH antagonist, cetrorelix, to ooctye donors simplifies oocyte donation.
BACKGROUND We report our experience on the efficacy of a new regimen of the GnRH antagonist, cetrorelix, and recombinant FSH, Gonal-F, for controlled ovarian stimulation in a donor oocyte programme. METHODS AND RESULTS Six oocyte donors were commenced on Gonal-F (150 IU) and two on Gonal-F 225 IU daily on day 4 together with cetrorelix 0.25 mg daily on day 8 until the day of administration of...
متن کاملGnRH agonist versus GnRH antagonist in oocyte donation cycles: a prospective randomized study.
BACKGROUND The specific role of LH in folliculogenesis and oocyte maturation is unclear. GnRH antagonists, when administered in the late follicular phase, induce a sharp decrease in serum LH which may be detrimental for IVF outcome. This study was performed to evaluate whether the replacement of GnRH agonist (triptorelin) by a GnRH antagonist (ganirelix; NV Organon) in oocyte donation cycles ha...
متن کاملComparison between a GnRH antagonist and a GnRH agonist flare-up protocol in oocyte donors: a randomized clinical trial.
BACKGROUND Little information is available on the outcome of controlled ovarian hyperstimulation (COH) using GnRH antagonist in oocyte donation cycles especially in comparison with the short GnRH agonist protocol. This study was aimed at comparing the two stimulation protocols in oocyte donation (OD) cycles. METHODS A total of 113 donors randomly received COH using either GnRH antagonist or G...
متن کاملP-2: Evaluation of Apoptosis in Germ Cells, following Treatment with Vincristine and Cetrorelix (GnRH Antagonist)
Background: Infertility problem affects young couples. One of the known causes of spermatogenic disorder is chemotherapy in patients with cancer. Since dividing cells are mainly affected by anticancer drugs, the aim of the present study is to investigate the preventive effect of GnRH antagonist on spermatogenic cell apoptosis produced by anticancer drug. Materials and Methods: In the present st...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2003
ISSN: 1460-2350
DOI: 10.1093/humrep/deg271